According to several other previous reports, positive expression of TFE3 was associated with clinical paremeters and its prognosis.[20–22] As reported by Mir et al,[22] 7 of 8 TFE3-positive patients had lymph node metastasis, whereas 5.8% of TFÊ3-negative patients had lymph node metastasis and cava thrombus. Here, TFE3 is linked to metastatic malignant neoplasm in the lymph nodes.