CDX2 and colorectal carcinoma: Specifically, the standard CRC chemotherapeutic drug irinotecan was more effective in CDX2‐negative cell lines (Wilcoxon rank‐sum test, P = 0.008 (with FDR adjustment, P = 0.02); Fig. 4C), while the differences observed for fluorouracil and oxaliplatin were not statistically significant.