Tubulin polymerization-promoting protein, a protein involved in the maintenance of microtubule network stability,105,106 plays also a role in SNCA aggregation and co-localizes with aggregated SNCA in Lewy bodies inclusions in a group of α-synucleinopathies.30 We found tubulin polymerization-promoting protein in ORG and ORG-NM samples, suggesting its possible involvement in NM synthesis and NM-containing organelle formation due to its reported role in initiating the formation of cellular aggresome-like structures and inclusion bodies.105. The gene discussed is SNCA; the disease is synucleinopathy.