The levels of IL-1β in plasma were significantly higher (p < 0.0001) in patients (252.3 ± 6.49 pg/ml) as compared to healthy controls (127.6 ± 3.98 pg/ml), whereas plasma levels of NO were significantly lower (p < 0.0001) in UPEC infected UTI patients (60.29 ± 1.1 μM) as compared to healthy controls (106.3 ± 8.75 μM). The gene discussed is IL1B; the disease is bacterial urinary tract infection.