DNER and breast carcinoma: Breast cancer cells (MCF7, SKBR3), on the other hand, were sensitive to JQ1 (IC50 range 0.33–1.10 μM), but not to dBET1 (IC50 range 2.19–5.90 μM), whereas ovarian cancer cells (A2780, SKOV3) were sensitive to both types of BET antagonists (IC50 range 0.45–1.49 μM, Table 1).