GPNMB and neoplasm: Of these, transmembrane glycoprotein NMB (Gpnmb), low affinity immunoglobulin gamma Fc region receptor II (Fcgr2), H-2 class I histocompatibility antigen, alpha chain, and programmed cell death 1 ligand 2 (Pdcd1lg2) are directly involved in tumor immune evasion.