BRAF and atrial fibrillation: All the 8 mutations detected at >1000×cov and <5% AF (13.3%) and consisting of 1 KRAS, 3 NRAS, 4 BRAF mutations, were detected in 6 mutant samples harboring ≥2 mutations: 5 associated to KRAS mutations detected at >1000×cov and >5% AF; 1 (1.6%) mut sample with a NRAS c.182 A>G (Q61R) associated to BRAF c.1796 C>T (T599I) mutation represented the only sample with mutations detected at >1000×cov and <5% AF.