To further evaluate the role of the ATP competitive inhibitors in HCC as a function of CD44 expression, we selected three CD44high (SNU423, SNU449 and Sk-Hep-1) and three CD44low (Huh7, PLC/PRF/5, HepG2) cell lines (Supplementary Figure 2). The gene discussed is CD44; the disease is hepatocellular carcinoma.