GPER1 and neoplasm: Low GPER mRNA expression was associated with P53 mutation status (χ2=19.7; d.f.=1; P<0.001 and χ2=33.4; d.f.=1; P<0.001 for probe 1 and 2 respectively), stage (χ2=11.4; d.f.=4; P=0.023 and χ2=11.1; d.f.=4; P=0.025 for probe 1 and 2 respectively), larger tumour size (χ2=16.2; d.f.=1; P<0.001 and χ2=16.9; d.f.=1; P<0.001 for probe 1 and 2 respectively), higher tumour grade (χ2=83.0; d.f.=2; P<0.001 and χ2=87.3; d.f.=2; P<0.001 for probe 1 and 2 respectively) and ER negative tumours (χ2=119.1; d.f.=1; P<0.001 and χ2=130.3; d.f.=1; P<0.001 for probe 1 and 2 respectively).