Although we have seen an increased expression of P-selectin and the fibrinogen-binding to the GPIIb/IIIa on platelets of GBM at baseline and after in vitro platelet stimulation, the formation of platelet-monocyte conjugates was rather decreased in GBM patients, which was most pronounced after the strong in vitro stimulation of platelets with TRAP. The gene discussed is SELP; the disease is glioblastoma.