However, the formation of PMC was clearly and almost statistically significant reduced in GBM patients after in vitro platelet stimulation with TRAP (GBM: median 128.5 MFI, range from 59 MFI to 378 MFI/CON: median 182.3MFI, range from 50 MFI to 935 MFI/ p = 0.06) (Figure 5A). The gene discussed is CD40LG; the disease is glioblastoma.