PDE6B and retinitis pigmentosa 1: Despite the effect of immune therapy was not as remarkable as that of gene therapy in the rd1 mouse, suppression of neuroinflammation by AAT would provide a suitable microenvironment for cell survival and a stable treatment window for other therapies, considering the fact that neuroinflammation is associated with various type of RP, it serves as a hallmark of common pathological process of RP.