MT-ND6 and cancer: Accumulating evidence highlighted the importance of mitochondria in cancer cell metastasis.11, 12, 22, 32 Whether it was a mutation in NADH dehydrogenase subunit 6 (ND6),32 an overexpression of the survival protein survivin,12 or ETC overload and partial ETC inhibition,11 increased mtROS and associated redox deregulation was suggested as underlying mechanisms of metastasis promotion.