ANO1 and gastrointestinal stromal tumor: ANO1 overexpression is involved in the tumorigenesis of epithelial cancers including oral cancer4, gastrointestinal stromal tumor (GIST)5, head and neck squamous cell carcinoma (HNSCC)6, prostate cancer7 and hyperplasia8, breast cancer9, colorectal cancer10, glioma11, esophageal squamous cell carcinoma12, pancreatic ductal adenocarcinoma13, lung cancer14, and hepatocellular carcinoma15.