To directly compare to the IPMN types, one study demonstrated that while more than half of non-invasive MCN cases were MUC2+ or CDX2+, with 40% being MUC2+ and CDX2+, all invasive cases (n = 3) were MUC1+, MUC2- and only one case was CDX2+ [58]. This evidence concerns the gene MUC2 and pancreatic intraductal papillary-mucinous neoplasm.