STAT3 and neoplasm: In agreement with these results, we have also found a significant inhibitory effect on TNBC metastasis by the following manipulations: depleting IL-6 in the tumor-conditioned medium injected into mice prior to tumor inoculation using an anti-IL-6 antibody, inhibiting CCL5 by maraviroc, inhibiting VEGF by an anti-VEGF antibody, and inhibiting STAT3 by S3I-201 [8].