Surprisingly, via GTT, we found that, after HFD feeding, the autophagy-hyperactive Becn1FA/+ or Becn1FA/FA mice have exacerbated glucose intolerance compared to WT mice, which is similar to findings with the autophagy-deficient Becn1+/− KO mice (Figure 2B). Here, BECN1 is linked to Glucose intolerance.