± 0.81, p<0.01) and the rate-limiting gluconeogenic enzymes Phosphoenolpyruvate Carboxykinase 1 (PCK1) (1.40 ± 0.6 vs 1.02 ± 0.15, p<0.05) and glucose-6-phosphatase catalytic subunit (G6Pc) (2.38±1.55 vs 1.0 ±0.46, p<0.01) was observed in IUGR pups. The gene discussed is PCK1; the disease is fetal growth restriction.