At one hundred and five days after birth (PND105), IUGR rats showed no significant difference in weight when compared to SHAM animals (mean weight ± SD: 421.9±146.7 versus 443.76± 130.4 g, Fig 2A) and did not display significant differences in the blood levels of glucose, insulin, leptin or free fatty acids (FFAs) (Fig 2B). This evidence concerns the gene LEP and fetal growth restriction.