At first, we confirmed that ZDFRs, an animal model of type 2 diabetes, showedsignificant increase of HbA1c, urinary albumin and L-FABP excretion, histologicallyrenal injuries including fibrosis and tubular cell damage, and urinary 8-OHdGexcretion was also significantly elevated, which is closely related to high glucoselevels. The gene discussed is FABP1; the disease is type 2 diabetes mellitus.