These microbicidal responses are often orchestrated through classical immune signaling pathways like immunodeficiency (IMD), Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) and Toll signaling pathways (Hoffmann et al., 1999; Irving et al., 2001; Hoffmann and Reichhart, 2002; Hoffmann, 2003; Myllymäki et al., 2014). This evidence concerns the gene SOAT1 and Immunodeficiency.