CD40 and myeloid sarcoma: Since genetic factors were demonstrated to affect the susceptibility to MS, series of genome-wide association studies have been performed and multiple SNPs that are associated with MS have been identified, including polymorphisms in genes for interleukin 2 receptor alpha, interleukin 7 receptor, rs703842 and rs10876994 on chromosome 12, and CD40 on chromosome 20 [76, 77].