TGFB1 and telomere syndrome: We also found that the transcriptional level of IL-33 was negatively correlated with that of TGF-β1, an immunosuppressive cytokine, and chemokines that recruit Tregs and myeloid-derived suppressor cells (MDSCs), indicating that the IL-33/ST2 axis may also contribute to inhibiting the production of TGF-β1 and reducing the infiltration of Tregs and MDSCs in STS.