To investigate whether vaccination with phage particles would protect against infection with T. cruzi, we first immunized B6 (WT) mice with the model antigen ovalbumin (OVA257–264) SIINFEKL peptide, a known H-2Kb-restricted epitope, as an N-terminal fusion with the pVIII phage protein (fd-OVA). The gene discussed is ELP1; the disease is infection.