HTR1A and schizophrenia: One study reported an increase in 5-HT1A availability in the medial temporal cortex of schizophrenia patients (56), whereas another reported a decrease in the amygdala (57); the remaining two reported no difference in 5-HT1A availability between schizophrenia patients and healthy controls, although a meta-analysis of postmortem studies found an elevation in prefrontal 5-HT1A in schizophrenia (53).