Prognostic factors such as tumor stage and tumor markers [e.g., prostate-specific antigen (PSA), alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG)] have been shown to correlate with the course of disease and/or prognosis (Mead and Stenning, 1997; Gospodarowicz and O’Sullivan, 2003). Here, AFP is linked to neoplasm.