Interestingly, we found the rate of meningitis occurrence, defined as positive CSF culture with meningeal inflammation, was reduced to 25% in Caspr1 eKO mice (n = 16), which is significantly lower than the 61% in control mice (n = 18) (P < 0.05, χ2 test, Fig. 2c, d). Here, CNTNAP1 is linked to infectious meningitis.