Notably, 43.5% of seminiferous tubules displayed maturation arrest at round spermatid stage in FancmΔC/ΔC mice, which has not been mentioned in Fancm mutant mice18,19 or reported in any other FA mouse models,19–22 suggesting that this role of FANCM could be independent of the canonical FA pathway. The gene discussed is FANCA; the disease is Friedreich ataxia.