GPT and infection: In addition, in 28 patients with an increasing trend in serum bilirubin (hence, closer to the beginning of the infection) the peak alteration of biochemical parameters correlated with the time to HBsAg clearance (AST R2 = 0.318, p = 0.0082, ALT R2 = 0.145, p = 0.0263; total bilirubin R2 = 0.222, p = 0.011, Spearman correlation).