TGIF2 and neoplasm: For tumor tissues of blank group, TGIF2 group, and TGIF2 + mimics group, TGIF2 mRNA and protein relative expression was significantly higher than than of blank group (P<0.05), while no statistically significant difference was observed between TGIF2 + mimics group and blank group in TGIF2 mRNA and protein relative expression (Figure 4A,B).