G6PD and hyperinsulinemic hypoglycemia, familial, 4: Severe INH was associated with: prematurity (< 32 weeks, Adjusted Odds Ratio (AOR) 3.3; 95% CI 1.6–6.6 and 32 to 37 weeks, AOR 2.2; 95% CI 1.6–3.1), Glucose-6-phosphate dehydrogenase deficiency (G6PD) (AOR 2.3; 95% CI 1.6–3.3), potential ABO incompatibility (AOR 1.5; 95% CI 1.0–2.2) and late presentation (AOR 1.8; 95% CI 1.3–2.6).