TGFB1 and Duchenne muscular dystrophy: As previously reported for DMD [26,27], we observed that TGF-β1 was mainly expressed in the sarcoplasm or subjacent to sarcolemma of some non-necrotic muscle fibers (Figure 6): in particular, in dystrophic LMNA-RM muscles TGF-β1 expression seems to be homogeneously distributed in the sarcoplasm (Figure 6, upper panel); in myopathic LMNA-RM muscles it seems to be more located in the periphery of muscle fibers in close proximity to CD68 positive macrophages (Figure 6, middle panel).