Interestingly, another gene coding for a subunit of the SWI/SNF complex (ARID1A/BAF250A) has been found to have frameshift or nonsense mutations in up to 10% of colon tumors [40], suggesting that abnormalities in ARID1A protein may have a role colon carcinogenesis. The gene discussed is ARID1A; the disease is colonic neoplasm.