We have recently demonstrated that CIP2A is overexpressed and positively associated with HPV‐16E7 in cervical cancer tissues and cells, and the expression of CIP2A is correlated with tumour grade.13 However, as another important oncoprotein encoded by HPV, how 16E6 protein regulates CIP2A and the role of CIP2A in 16E6‐expressing cells remain unclear. Here, CIP2A is linked to neoplasm.