CADM1 and pulmonary emphysema: We recently found lung-epithelial cell adhesion molecule 1 (CADM1), also known as tumor suppressor in lung cancer 1 (TSLC1) and nectin-like molecule 2 (Necl-2), to be involved in the development of emphysema (Mimae et al., 2014; Hagiyama et al., 2015).