TP53 and acute promyelocytic leukemia: High levels of the SnoN/PML (promyelocytic leukemia) complex stabilize p53 and induce senescence in MEFs; whereas, the SnoN/p53 complex enhances p53-mediated transcription in MEFs.45,224 SnoN stabilizes TAZ protein by inhibiting its phosphorylation, which enhances TAZ/TEAD complex target gene expression during cell proliferation.