In contrast, two SNPs (at NCKAP5 and PMM2), which were reported with suggestive evidence of association with POAG in previous studies of Asian individuals10,12, were associated with POAG in neither the current GERA multiethnic meta-analysis (P > 0.05), nor in the East Asian race/ethnicity group. Here, NCKAP5 is linked to open-angle glaucoma.