However, IL-6 can also signal through an alternate pathway to promote regenerative and anti-inflammatory signaling in the liver37–39, effects that would be consistent with reduced parasitemia in ABA-treated mice as well as reduced hepatomegaly at day 9 PI (Fig. 3A) and recovery of BUN in ABA-treated, infected mice to control levels at day 11 PI (Fig. 5A). Here, IL6 is linked to parasitic infectious disease.