To determine the possible role of mPGES-1 in the production of PGE2 and suppression of motility in the post-BO state, we treated rats with daily administration of a specific mPGES-1 inhibitor Cay 10526 at 2.5 mg/kg i.p24,25,27. The gene discussed is PTGES; the disease is bronchiolitis obliterans syndrome.