PPARA and hereditary disease: The activation of PPAR-α with the inhibition of DNL and the increase of the n-3 HUFA score may, at least in part, explain the anti-neuroinflammatory effects exerted by CLA in X-linked adrenoleucodystrophy, a genetic disorder characterized by an impaired peroxisomal beta-oxidation [58,59], confirming that PPAR-α activation can also play an important role in the prevention of neurodegenerative pathologies [60,61].