Previous evidence demonstrated that KP extract significantly suppressed the phosphorylation of PI3K, AKT, ERK1/2, and Elk1 in HeLa cells [10], thus we hypothesized whether KP extract can suppress the activation of ERK1/2 and AKT signaling in high grade serous ovarian cancers. This evidence concerns the gene MAPK3 and ovarian serous adenocarcinoma.