Although circRNAs were suggested to be associated with some kinds of common human cancers, such as circRNAs TCF25 and MYLK in bladder cancer [22, 23], hsa_circ_0005986 and hsa_circ_0004018 in hepatocellular carcinoma [22, 24] and hsa_circ_0000520 in gastric cancer [25], little is known about the roles circRNAs play in lung cancer. This evidence concerns the gene TCF25 and hepatocellular carcinoma.