Considering that microRNAs constitute complex multiple network of signaling pathways [60], relative expression levels of miR-197 may indicate inhibition of NF-κB/Mcl-1 and STAT3 signaling in ABC DLBCL, suggesting the possible role of miR-197 as a biomarker of progression in DLBCL, especially in the ABC subtype. The gene discussed is MCL1; the disease is diffuse large B-cell lymphoma.