Considering that microRNAs constitute complex multiple network of signaling pathways [60], relative expression levels of miR-197 may indicate inhibition of NF-κB/Mcl-1 and STAT3 signaling in ABC DLBCL, suggesting the possible role of miR-197 as a biomarker of progression in DLBCL, especially in the ABC subtype. This evidence concerns the gene NFKB1 and aneurysmal bone cyst.