Interestingly, several of these genes (e.g. ELTD1, SDHB, SEPW1, SLC17A7, SZRD1, THAP3, ZBTB17) are likely to push, whereas other genes (e.g. CAP1, HBXIP, KLK6, PARK7, PTAFR) might restrict oligodendroglioma development. The gene discussed is PTAFR; the disease is oligodendroglioma.