Interestingly, several of these genes (e.g. ELTD1, SDHB, SEPW1, SLC17A7, SZRD1, THAP3, ZBTB17) are likely to push, whereas other genes (e.g. CAP1, HBXIP, KLK6, PARK7, PTAFR) might restrict oligodendroglioma development. The gene discussed is THAP3; the disease is oligodendroglioma.