An elevated NLR was significantly associated with the tumour size (P < 0.001), Fuhrman-grade (P = 0.011), TNM stage (P < 0.001), pT status (P = 0.001), pN status (P < 0.001), tumour thrombus (P = 0.014), CRP/Alb (P < 0.001), PLR (P = 0.001), LDH (P = 0.014) and proteinuria (P < 0.013). The gene discussed is CRP; the disease is neoplasm.