KLK3 and posterior cortical atrophy: Univariate analysis indicated that gland volume (P = 0.047, HR 3.668), MAB pattern (P = 0.031, HR 1.492), PPB addition (P = 0.001, HR 2.888), clinical stage (P = 0.041, HR 4.737), Gleason score (P = 0.013, HR 5.711), baseline PSA (P = 0.019, HR 2.622), Memorial Sloan-Kettering Risk Classification Standard score (P = 0.027, HR 1.772), PSA nadir (P = 0.041, HR 1.323), time to PSA nadir (P = 0.032, HR 2.116), PSADT (P = 0.048, HR 1.863), and PSA reduction (P = 0.006, HR 3.677) were significant predictors of BRFS in patients with localized, high-risk PCa.