More recently, we demonstrated that WIP is not only highly expressed in some tumour types, but is also essential for maintenance of tumour subpopulations denoted as “cancer stem cells” (CSCs) or “tumour-initiating cells” (TICs) [33], a phenotype frequently responsible for advancement to more aggressive stages of disease, at least in some tumour types [34]. The gene discussed is WIPF1; the disease is neoplasm.