IL1A and heart disorder: It is worthwhile to note that the pro-inflammatory response, is known to be increased and to positively correlate with the severity of the cardiac disease [1–3]; It has been recently suggested that pro-inflammatory mediators are able to upregulate RAS and that the interplay between TNFα and AngII is mediated by increased production of reactive oxygen species (ROS) through NOX pathways.[35] In the current study we have identified modified expression of pro-inflammatory cytokines (IL-1α and TNFα) and the anti-inflammatory agent IL-10.