AGT and chronic kidney disease: In order to test this hypothesis, short-term (11 weeks) CKD rats, that were documented with higher levels of plasma AngII compare to control (1.53±0.09pg/ml versus 0.69±0.04pg/ml, n = 6/group, p<0.0001; data not shown), were treated with Losartan, an AngII receptor blocker (ARB).