SLC25A1 and cancer: Therefore, in the present study we aimed to explore the role of SLC25A1 for the increased antioxidant capacity of cancer cells adapted to chronic cycling severe hypoxia/reoxygenation stress and the use of SLC25A1 inhibition as novel strategy for radiosensitization of NCI-H460 lung adenocarcinoma cells exposed to acute or chronic cycling severe hypoxia.