Similarly, TB40E IE+ M2-Mφ (Figures 2I,J) maintained MHC class I levels that were comparable to mock-infected cells, while ΔUS2–11 IE+ Mφ expressed higher MHC class I levels, thus confirming that also in M2-Mφ the four immune evasive genes counterbalance MHC upregulation induced by infection. The gene discussed is HLA-C; the disease is infection.