Data from the Swedish registries from 2009 to 2013 in 1 04 012 patients showed that ticagrelor was the preferred antiplatelet agent of choice in patients who had acute coronary syndromes and who underwent angiography (ticagrelor 54%, clopidogrel 26%, prasugrel 1%, and no P2Y12 inhibitor 18%).7 Similar to the trend in our report, data analyzed from Australia from 2009 to 2013 show that the majority of patients were treated with clopidogrel (72%) in preference to prasugrel (14%) and ticagrelor (14%), albeit with increasing use of ticagrelor towards the end of 2013. Here, P2RY12 is linked to acute coronary syndrome.