In a pilot study, stage III colon cancer patients receiving standard OxP/capecitabine chemotherapy were vaccinated at the same time with keyhole limpet hemocyanin (KLH) and carcinoembryonic antigen (CEA)-peptide pulsed DCs, and enhanced T-cell reactivity upon OxP administration was observed48. The gene discussed is CEACAM5; the disease is malignant colon neoplasm.